Saltar al contenido

NoticiasContactoNoticiasContacto

Buscar cursos

up-menu

Buscar:

Facebook page opens in new window X page opens in new window Instagram page opens in new window YouTube page opens in new window Linkedin page opens in new window Whatsapp page opens in new window

Buscar cursos

up-menu

Buscar:

Facebook page opens in new window X page opens in new window Instagram page opens in new window YouTube page opens in new window Linkedin page opens in new window Whatsapp page opens in new window

Escuela Andaluza de Salud Pública

La Escuela Andaluza de Salud Publica (EASP) es una Empresa Publica dependiente de la Consejeria de Salud de la Junta de Andalucia, creada para la coordinacion y desarrollo de la formacion, la consultoria, la investigacion y la cooperacion internacional en los campos de Salud Publica y Gestion de Servicios Sanitarios

Iniciativa de la Association of School & Programs of Public Health (ASPPH) para dar a conocer el concepto de Salud Pública

La Escuela ▾
Consultoría
Formación ▾
Investigación
Salud Internacional
- EASP Centro Colaborador OMS
Áreas y Observatorios▾
Conocimiento abierto
Intranet

La Escuela ▾
Consultoría
Formación ▾
Investigación
Salud Internacional
- EASP Centro Colaborador OMS
Áreas y Observatorios▾
Conocimiento abierto
Intranet

NoticiasContacto

Buscar cursos

up-menu

Buscar:

Facebook page opens in new window X page opens in new window Instagram page opens in new window YouTube page opens in new window Linkedin page opens in new window Whatsapp page opens in new window

Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans

Estás aquí:

Inicio
Project
Circulating copper and zinc levels…

CirculatingCoper

Background: Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.

Methods: A nested case–control study was conducted within the European Prospective Investigation into Cancer and Nutrition cohort. Serum zinc and copper levels were measured in baseline blood samples by total reflection X-ray fluorescence in cancer cases (HCC n=106, IHDB n=34, GBTC n=96) and their matched controls (1:1). The Cu/Zn ratio, an indicator of the balance between the micronutrients, was computed. Multivariable adjusted odds ratios and 95% confidence intervals (OR; 95% CI) were used to estimate cancer risk.

Results: For HCC, the highest vs lowest tertile showed a strong inverse association for zinc (OR=0.36; 95% CI: 0.13–0.98, P_trend=0.0123), but no association for copper (OR=1.06; 95% CI: 0.45–2.46, P_trend=0.8878) in multivariable models. The calculated Cu/Zn ratio showed a positive association for HCC (OR=4.63; 95% CI: 1.41–15.27, P_trend=0.0135). For IHBC and GBTC, no significant associations were observed.

Conclusions: Zinc may have a role in preventing liver-cancer development, but this finding requires further investigation in other settings.

Ver artículo completo

Categoría: Artículos Científicos10/02/2017

Compartir este artículo:

Share on FacebookShare on Facebook Share on XShare on X Share on LinkedInShare on LinkedIn Share on WhatsAppShare on WhatsApp

Últimas noticias

Un estudio del ibs.GRANADA analiza las desigualdades socioeconómicas en las creencias y conocimiento sobre el cáncer en la población española
04/04/2025
Dos nuevos casos de sarampión elevan a 49 el cómputo total en Andalucía y a seis los brotes activos
04/04/2025
La EASP acoge una jornada internacional sobre la ética de la investigación frente a los avances en neurotecnología e inteligencia artificial
04/04/2025

Jornadas y Eventos

Último en Easp a la carta

Todas las noticias

Todas las jornadas

Ver toda la carta

18011 Cuesta del Observatorio 4, Campus Universitario de Cartuja, Granada (Spain)
+34958027400 - comunicacion.easp@juntadeandalucia.es
Facebook

Twitter

YouTube

Instagram

Canales de denuncia MRR
Política de Privacidad
Aviso Legal
Identificarse
Buscar cursos

———bottom-menu