The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition

Background: Higher coffee intake has been purportedly related to a lower risk of liver cancer. However, it remains unclear whether this association may be accounted for by specific biological mechanisms. Objective: We aimed to evaluate the potential mediating roles of inflammatory, metabolic, liver injury, and iron metabolism biomarkers on the association between coffee intake and…

Description of indexes based on the adherence to the ‪Mediterranean‬ ‪dietary‬ pattern: a review

Introducción: los índices de calidad la de dieta son herramientas que sirven para cuantificar el cumplimiento de un patrón dietético definido. Estos índices son una medida combinada de factores dietéticos (grupos alimenticios, alimentos, nutrientes y ratios) y/o estilos de vida. La dieta mediterránea (DM) es un patrón dietético que se caracteriza por sus efectos positivos…

Recesión bibliográfica: Health technology assessment and health policy today: a multifaceted view of their unstable crossroads

Recensión bibliográfica Del Llano Señarís JE, Campillo-Artero C, directores. Health technology assessment and health policy today: a multifaceted view of their unstable crossroads. En: Ortún V, director. Colección «Economía de la salud y gestión sanitaria». Madrid: Springer Healthcare Communications Ibérica; 2014. 156 p. ISBN: 978-84-940118-5-6

Background: Studies of the role of dietary factors in epithelial ovarian cancer (EOC) development have been limited, and no specific dietary factors have been consistently associated with EOC risk. Objective: We used a nutrient-wide association study approach to systematically test the association between dietary factors and invasive EOC risk while accounting for multiple hypothesis testing…

Vegetable and fruit consumption and the risk of hormone receptor–defined breast cancer in the EPIC cohort

Background: The recent literature indicates that a high vegetable intake and not a high fruit intake could be associated with decreased steroid hormone receptor–negative breast cancer risk. Objective: This study aimed to investigate the association between vegetable and fruit intake and steroid hormone receptor–defined breast cancer risk. Design: A total of 335,054 female participants in…

A systematic review and meta-analysis of HIV prevention interventions for socioeconomically disadvantaged ethnic minority women in OECD member countries

Background Recently there have been many encouraging developments in the global effort to combat HIV and AIDS. The latest data collected by UNAIDS on the status of the disease showed a 33% reduction in new HIV cases since 2001 and a decrease of 700,000 deaths annually since the peak in 2005. 1 Within the 34…

La salud de las personas adultas afectadas por un proceso de desahucio

Objetivo Analizar el estado de salud percibida, y otros indicadores relacionados con la salud, en personas adultas de Granada que se encuentran en un proceso de desahucio de su vivienda habitual, de alquiler o en propiedad, en comparación con la salud de la población general andaluza. Métodos Estudio transversal mediante encuesta administrada por personal entrenado…

Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study

BACKGROUND: Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521 330 total participants (approximately 370 000 women)…

Epidemiological support for genetic variability at hypothalamic–pituitary–adrenal axis and serotonergic system as risk factors for major depression

Background: Major depressive disorder (MDD) is a serious, and common psychiatric disorder worldwide. By the year 2020, MDD will be the second cause of disability in the world. The Granad∑p study is the first, to the best of our knowledge, epidemiological study of mental disorders carried out in Andalusia (South Spain), being one of its…

Regional Versus Centralized Hta: Implications for the Assessment of Cancer Drugs

Different jurisdictions organize their health technology assessment (HTA) capacity in different ways. In theory, a centralized approach offers the potential to pool the scarce resources devoted to HTA and national recommendations can be issued to encourage a uniform development of services across the whole country. On the other hand, a regional approach could help in…