Arquitectura Sanitaria en el Sistema Sanitario Público de Andalucía

ARQUITECTURA SANITARIA EN EL SISTEMA SANITARIO PÚBLICO DE ANDALUCÍA GUÍA DE DISEÑO DE CENTROS DE ATENCIÓN PRIMARIA Esta Guía de Diseño tiene por objeto aportar información a los equipos profesionales que intervienen el diseño arquitectónico o remodelación de los centros de atención primaria del SAS. Está dirigida tanto a profesionales técnicos del ámbito de la…

Aromatic DNA adducts and breast cancer risk: a case-cohort study within the EPIC-Spain

Epidemiologic evidence linking environmental exposure to polycyclic aromatic hydrocarbons (PAH) with breast cancer is limited. Measurement of DNA adducts formed by aromatic compounds, including PAH, has been carried in breast tissue samples and white blood cells from women with breast cancer and different kinds of controls. However, these studies provide inconsistent results and bias cannot…

Are costs derived from diagnosis-related groups suitable for use in economic evaluations? A comparison across nine European countries in the European Healthcare and Social Cost Database

Background Economic evaluation of health technologies requires healthcare resources, procedures and services to be valued at their opportunity cost. In practice, many economic evaluation studies use official databases of hospital Diagnosis-Related Groups (DRGs) as inputs where unit costs are required. This study describes the available data on costs of hospital DRG from official, publicly available…

Approach to identifying research gaps on vector-borne and other infectious diseases of poverty in urban settings: scoping review protocol from the VERDAS consortium and reflections on the project’s implementation

Background This paper presents the overall approach undertaken by the “VEctor boRne DiseAses Scoping reviews” (VERDAS) consortium in response to a call issued by the Vectors, Environment and Society unit of the Special Programme for Research and Training in Tropical Diseases hosted by the World Health Organization. The aim of the project was to undertake…

Anticoncepción de urgencia y objeción de conciencia: un debate sin cerrar

El objetivo de este editorial es reflexionar sobre la anticoncepción de urgencia y las posibles implicaciones para la salud pública de la reciente Sentencia del Tribunal Constitucional (STC) sobre el recurso de amparo interpuesto por el cotitular de una oficina de farmacia por supuesta vulneración del derecho a la objeción de conciencia al haber sido…

Anticipated prehospital decision delay in response to different symptom clusters in acute coronary syndrome: Results from the Spanish Cardiobarometer study

Background and objective Reducing patient decision delay – the time elapsed between symptom onset and the moment the patient decides to seek medical attention – can help improve acute coronary syndrome survival. Patient decision delay is typically investigated in retrospective studies of acute coronary syndrome survivors that are prone to several biases. To offer an…

Anticipated help-seeking for cancer symptoms before and after the coronavirus pandemic: results from the Onco-barometer population survey in Spain

Background The patient interval—the time patients wait before consulting their physician after noticing cancer symptoms—contributes to diagnostic delays. We compared anticipated help-seeking times for cancer symptoms and perceived barriers to help-seeking before and after the coronavirus pandemic. Methods Two waves (pre-Coronavirus: February 2020, N = 3269; and post-Coronavirus: August 2020, N = 1500) of the Spanish Onco-barometer population survey were compared.…

Antibody responses to Helicobacter pylori and risk of developing colorectal cancer in a European cohort

Background: While Helicobacter pylori (H. pylori) is the major cause of gastric cancer, it has also been suggested to be involved in colorectal cancer (CRC) development. However, prospective studies addressing H. pylori and CRC are sparse and inconclusive. We assessed the association of antibody responses to H. pylori proteins with CRC in the European Prospective…

Antibody Response 3 Months after 2 Doses of BNT162b2 mRNA COVID-19 Vaccine in Residents of Long-Term Care Facilities

Background: Older adults living in long-term care facilities (LTCFs) are at increased risk for severe outcomes from COVID-19 and were identified as a priority group in COVID-19 vaccination strategies. Emerging evidence suggests vaccine effectiveness in LTCF populations, but data about median and long-term durability of immune response after vaccination are still limited. Objectives: In this…

Anti-CA15.3 and anti-CA125 antibodies and ovarian cancer risk: Results from the EPIC cohort

Background:Neoplastic and non-neoplastic events may raise levels of mucins, CA15.3 and CA125, and generate antibodies against them; but their impact on epithelial ovarian cancer (EOC) risk has not been fully defined. Methods:CA15.3, CA125, and IgG1 antibodies against them were measured in 806 women who developed EOC and 1,927 matched controls from the European Prospective Investigation…