A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study

Background Combinations of multiple fatty acids may influence cardiometabolic risk more than single fatty acids. The association of a combination of fatty acids with incident type 2 diabetes (T2D) has not been evaluated. Methods and findings We measured plasma phospholipid fatty acids by gas chromatography in 27,296 adults, including 12,132 incident cases of T2D, over…

A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk

Previous prospective studies assessing the relationship between circulating concentrations of vitamin D and prostate cancer risk have shown inconclusive results, particularly for risk of aggressive disease. In this study, we examine the association between prediagnostic concentrations of 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] and the risk of prostate cancer overall and by tumor characteristics.…

A cluster-randomized trial to reduce caesarean delivery rates in Quebec: cost-effectiveness analysis

Background Widespread increases in caesarean section (CS) rates have sparked concerns about risks to mothers and infants and rising healthcare costs. A multicentre, two-arm, cluster-randomized trial in Quebec, Canada assessed whether an audit and feedback intervention targeting health professionals would reduce CS rates for pregnant women compared to usual care, and concluded that it reduced…

A body shape index (ABSI) is associated inversely with post-menopausal progesterone-receptor-negative breast cancer risk in a large European cohort

Background Associations of body shape with breast cancer risk, independent of body size, are unclear because waist and hip circumferences are correlated strongly positively with body mass index (BMI). Methods We evaluated body shape with the allometric “a body shape index” (ABSI) and hip index (HI), which compare waist and hip circumferences, correspondingly, among individuals…

A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)…

A «tale of two countries»: narratives of hearts, patients and doctors in the Spanish press

In this article we explore how the Spanish written press – ABC, La Vanguardia, and Blanco y Negro – and the official newsreel No-Do, created and disseminated a narrative about heart transplantations at the end of the 1960s. We consider how Franco’s regime used Christiaan Barnard’s heart transplants to legitimize the Spanish dictatorship and as…

52Revista EspañoladeDrogodependencias 45 (1) 2020Consumo de psicofármacos en Andalucía. Un análisis de la Encuesta Andaluza de Salud desde la perspectiva de género

Introducción: En España el 16% de la población consume psicofármacos, ansiolíticos, hipnóti-cos y antidepresivos son los más frecuentes. La prevalencia de consumo es el doble en mujeres que en hombres para todos los rangos de edad. Diversos autores y autoras indican que esta diferencia puede deberse a roles y estereotipos de género.Objetivo: Determinar la prevalencia…

2015 Beers Criteria and STOPP v2 for detecting potentially inappropriate medication in community-dwelling older people: prevalence, profile, and risk factors

Purpose To comparatively assess the prevalence rates of potentially inappropriate medications (PIMs) obtained by the former and latest versions of American Geriatrics Society Beers Criteria (AGS BC) and screening tool of older person’s potentially inappropriate prescriptions (STOPP), and analyze the factors of influence on PIM. Methods Cross-sectional study including 582 community-dwelling older adults over the…

«Vísteme despacio que tengo prisa». Un análisis ético de la vacuna contra la COVID-19: fabricación, distribución y reticencia

La llegada de una vacuna contra el SARS-CoV-2 que pueda frenar la expansión de la infección se ha postulado como la respuesta definitiva para frenar la pandemia de COVID-19. Lejos de ser una solución libre de conflictos éticos, la introducción de una nueva vacuna en la práctica de la salud pública, y que se haga…