Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis

Purpose To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the consumption of…

The impact of COVID-19 pandemic on out-of-hospital cardiac arrest: an individual patient data meta-analysis

Aim Prior studies have reported increased out-of-hospital cardiac arrests (OHCA) incidence and lower survival during the COVID-19 pandemic. We evaluated how the COVID-19 pandemic affected OHCA incidence, bystander CPR rate and patients’ outcomes, accounting for regional COVID-19 incidence and OHCA characteristics. Methods individual patient data meta-analysis of studies which provided a comparison of OHCA incidence…

Comparative effects of different types of exercise on health-related quality of life during and after active cancer treatment: A systematic review and network meta-analysis

Background The positive influence of most types of exercise has been reported repeatedly, but what the most effective exercise approaches are for improving health-related quality of life (HRQoL) in people with cancer remains unknown. The aim of this systematic review and network meta-analysis was to synthesize the evidence from intervention studies to assess the effects…

Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study

Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited observational evidence, we investigated whether prediagnostic Se status and/or variants in the selenoprotein genes are associated with BC risk in a large European cohort. Se status was assessed by plasma measures of Se and its major circulating proteins, selenoprotein P (SELENOP) and glutathione…

Use of psychological interventions among healthcare workers over the 2-year period following the COVID-19 pandemic: A longitudinal study

Introduction Although healthcare workers (HCWs) have reported mental health problems since the beginning of the COVID-19 pandemic, they rarely use psychological support. Here, we described the use of psychological support among HCWs in Spain over the 2-year period following the initial pandemic outbreak and explore its association with workplace- and COVID-19-related factors measured at baseline,…

Renal tubular dysfunction in greenhouse farmers exposed to pesticides unveiled by a panel of molecular biomarkers of kidney injury

Growing evidence suggests that chronic exposure to pesticides may cause adverse effects on the health of the exposed population leading to organ-specific toxicity, including kidney damage. Traditional markers used to assess renal function (glomerular filtration rate (GFR), and serum creatinine and cystatin C –Cys-C–) are inadequate to evaluate a potential subclinical renal impairment linked to…

Salud comunitaria. Innovando en la formación de residentes de medicina familiar y comunitaria

Objetivo Conocer las opiniones de los agentes implicados en la formación de residentes de medicina familiar y comunitaria para mejorar el proceso formativo del «Proyecto de Apoyo a la Revitalización de la Atención Primaria; Activos para la Salud Comunitaria» (PARAC) teniendo en cuenta su adecuación, contextualización y las metodologías utilizadas. Método Estudio cualitativo interpretativo-explicativo de…

Prevención del suicidio. Una perspectiva salubrista. De lo individual a lo colectivo

El suicidio me cuestiona individual y colectivamente. Personal y profesionalmente. Emocional y éticamente. Física y socialmente. Y, desde luego, espiritualmente. Y me alegra muchísimo que desde la salud pública (a la que nada humano le es ajeno) ya se estén poniendo en marcha acciones de todo tipo dirigidas a lograr una prevención eficaz y sostenible…

Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries

Purpose Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ischaemic and haemorrhagic stroke in the EPIC study. Methods We analysed data from 356,142 participants from seven European countries. Dietary intakes of 19 individual…

Epidemiology of human papillomavirus-associated anogenital cancers in Granada: a three-decade population-based study

Introduction: HPV infection is a common risk factor for all anogenital cancers. However, there are important differences in the epidemiology of anogenital cancers and these have not been compared considering diverse epidemiological indicators over a long period of time. To fill this gap, we investigated incidence, mortality, and survival trends of anogenital cancers over a…