Importance Low-density lipoprotein cholesterol (LDL-C)–lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. Alleles near HMGCR are associated with a higher risk of type 2 diabetes, similar to the increased incidence of new-onset…
Se observa una asociación inversa significativa entre la actividad física y la obesidad Obesity, which in itself is a long-term disease, is at the same time a risk factor in the development of serious pathologies such as ischaemic heart disease, hypertension, hypercholesterolaemia and respiratory insufficiency.1 In developed countries, the prevalence of this disease has risen…
La incorporación del modelo de activos para la salud en las intervenciones de salud comunitaria/promoción de la salud puede reforzar aspectos relacionados con la equidad, la orientación a los determinantes sociales, la intersectorialidad y la participación en dichas intervenciones.
Carta al director de la profesora de la EASP, María del Mar García Calvente sobre los efectos del levonorgestrel en la anticoncepción de emergencia Sr. Director: Agradecemos el interés mostrado por Alegre del Rey et al. por nuestro editorial Anticoncepción de urgencia y objeción de conciencia: un debate sin cerrar1. Afirman estos autores que existe…
Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497…
Objective There is uncertainty about the direction and magnitude of the associations between parity, breastfeeding and the risk of coronary heart disease (CHD). We examined the separate and combined associations of parity and breastfeeding practices with the incidence of CHD later in life among women in a large, pan-European cohort study. Methods Data were used…
Objetivo Conocer la percepción y autovaloración de los y las responsables de equipos sanitarios de Andalucía sobre el liderazgo. Material y métodos Diseño exploratorio descriptivo mixto cuantitativo-cualitativo, llevado a cabo entre 2013 y 2015, usando un cuestionario de elaboración propia y una entrevista semiestructurada. Emplazamiento: Andalucía. Participantes: total de responsables de las unidades de gestión…
Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Among 477 312 participants, intakes of 23…
Background: Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a disease. The association can be distorted further by mismeasured confounders, leading to invalid results and conclusions. It is, however, difficult to adjust for the bias in the association when there is…
Purpose Rare cancers represent 22% of all tumors in Europe; however, the quality of the data of rare cancers may not be as good as the quality of data for common cancer. The project surveillance of rare cancers in Europe (RARECARE) had, among others, the objective of assessing rare cancer data quality in population-based cancer…
