Combined Genome, Transcriptome and Metabolome Analysis in the Diagnosis of Childhood Cerebellar Ataxia

Ataxia in children is a common clinical sign of numerous neurological disorders consisting of impaired coordination of voluntary muscle movement. Its most common form, cerebellar ataxia, describes a heterogeneous array of neurologic conditions with uncountable causes broadly divided as acquired or genetic. Numerous genetic disorders are associated with chronic progressive ataxia, which complicates clinical management,…

Colaboración entre las revistas de salud pública en España

La historia de la salud pública en España ha sido escrita principalmente en dos revistas que actualmente siguen siendo un referente en su desarrollo académico y profesional. Con trayectorias dispares, la Revista Española de Salud Pública (1926) y Gaceta Sanitaria (1888) comienzan ahora una política de cooperación que pretende situar a la salud pública en la agenda…

Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition

n vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma; however, epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC…

Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study

Background:The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective:To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Design:Prospective cohort study. Setting:10 European countries. Participants:521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition). Measurements:Hazard ratios (HRs) and 95% CIs estimated…

Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Purpose Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition)…

Coffee and Tea Consumption and the Contribution of Their Added Ingredients to Total Energy and Nutrient Intakes in 10 European Countries: Benchmark Data from the Late 1990s

Background: Coffee and tea are among the most commonly consumed nonalcoholic beverages worldwide, but methodological differences in assessing intake often hamper comparisons across populations. We aimed to (i) describe coffee and tea intakes and (ii) assess their contribution to intakes of selected nutrients in adults across 10 European countries. Method: Between 1995 and 2000, a…

Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and…

Codificación CIE-9-MC

Los boletines de codificación en CIE-9-MC recogen las normas aplicables a la 7ª edición, de enero de 2010, de este sistema de clasificación de enfermedades. El presente boletín compendia las «Normas Generales de Codificación en CIE-9-MC» de uso en cualquier Capítulo de esta clasificación. Normas Generales. Edición 2010 1. Enfermedades Infecciosas y Parasitarias. Edición 2010…

Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study

Background Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we…

Clinical Outcomes of First-line Therapies for Advanced Non–Small Cell Lung Cancer A Systematic Review of Trials Published Between 2010 and 2020

Objectives: To analyze the evolution of clinical outcomes derived from clinical trials on first-line therapies for advanced or metastatic non–small cell lung cancer (NSCLC) published between 2010 and 2020, focusing on how these outcomes impact survival rates and management of patients. Methods: A systematic review of phase III and pivotal phase II clinical trials was…