The relationship between parental stress and psychological adjustment of the children: The role of parental psychological flexibility as a mediator

There is growing interest in parental psychological flexibility, understood as parents’ ability to enjoy an optimal relationship with their children by accepting their negative emotions and thoughts in the present moment, while remaining child-conscious, in value-based parenting. Parenting can sometimes be stressful, especially when faced with the varied and changing challenges of parenthood. Parental stress,…

The relationship between blood pressure and risk of renal cell carcinoma

Background The relation between blood pressure and kidney cancer risk is well established but complex and different study designs have reported discrepant findings on the relative importance of diastolic blood pressure (DBP) and systolic blood pressure (SBP). In this study, we sought to describe the temporal relation between diastolic and SBP with renal cell carcinoma…

The questionnaire design process in the European Human Biomonitoring Initiative (HBM4EU)

Background Designing questionnaires is a key point of epidemiological studies assessing human exposure to chemicals. The lack of validated questionnaires can lead to the use of previously developed and sub-optimally adapted questionnaires, which may result in information biases that affect the study’s validity. On this ground, a multidisciplinary group of researchers developed a series of…

The patient, diagnostic, and treatment intervals in adult patients with cancer from high- and lower-income countries: A systematic review and meta-analysis

Background Longer time intervals to diagnosis and treatment are associated with worse survival for various types of cancer. The patient, diagnostic, and treatment intervals are considered core indicators for early diagnosis and treatment. This review estimated the median duration of these intervals for various types of cancer and compared it across high- and lower-income countries.…

The Influence of Hormonal Factors on the Risk of Developing Cervical Cancer and Pre-Cancer: Results from the EPIC Cohort

Background In addition to HPV, high parity and hormonal contraceptives have been associated with cervical cancer (CC). However, most of the evidence comes from retrospective case-control studies. The aim of this study is to prospectively evaluate associations between hormonal factors and risk of developing cervical intraepithelial neoplasia grade 3 (CIN3)/carcinoma in situ (CIS) and invasive…

The impact of COVID-19 pandemic on out-of-hospital cardiac arrest: an individual patient data meta-analysis

Aim Prior studies have reported increased out-of-hospital cardiac arrests (OHCA) incidence and lower survival during the COVID-19 pandemic. We evaluated how the COVID-19 pandemic affected OHCA incidence, bystander CPR rate and patients’ outcomes, accounting for regional COVID-19 incidence and OHCA characteristics. Methods individual patient data meta-analysis of studies which provided a comparison of OHCA incidence…

The experience‐based format of probability improves probability estimates: The moderating role of individual differences in numeracy

People with low statistical numeracy have difficulties understanding numerical information. For instance, they often misunderstand the probability of experiencing side effects, which could reduce adherence to medical treatments. We investigated whether presenting information about probability using a method based on the direct experience of events influences the accuracy of probability estimates compared to viewing a…

The Efficiency of Increased HCV Testing and Treatment Strategies in Spain to Achieve Elimination Goals

Background In 2015, Spain launched a national eradication strategy for hepatitis C virus (HCV), resulting in the highest treatment rate in Europe and substantial reductions in HCV prevalence. However, to achieve the goal of HCV elimination, it is necessary to scale-up the diagnosis, treatment, and management of HCV infection. Objective Our aim was to assess…