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Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study

Artículos Científicos

Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). Measurements of waist circumference, triglycerides, high-density lipoprotein cholesterol (HDLC), systolic and diastolic blood pressure, glycated hemoglobin as components of MetS definition, and plasma total neopterin…

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Causal effects of lifetime smoking on breast and colorectal cancer risk: Mendelian randomization study

Artículos Científicos

Background: Observational evidence has shown that smoking is a risk factor for breast and colorectal cancer. We used Mendelian randomization (MR) to examine causal associations between smoking and risks of breast and colorectal cancer. Methods: Genome-wide association study summary data were used to identify genetic variants associated with lifetime amount of smoking (n=126 variants) and…

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Caregiving and Caregiver Health 1 Year into the COVID-19 Pandemic (CUIDAR-SE Study): A Gender Analysis

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The COVID-19 pandemic has highlighted the importance of informal care and shown that women continue to shoulder the brunt of responsibilities in this area. In this study, we analyzed differences in caregiving and self-perceived health in a group of informal male and female caregivers 1 year into the COVID-19 pandemic. We performed a cross-sectional survey…

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Cardiovascular diseases among diffuse large B-cell lymphoma long-term survivors in Asia: a multistate model study

Artículos Científicos, Cáncer, Investigación

Background We modeled the clinical course of a cohort of diffuse large B-cell lymphoma (DLBCL) patients with no prior cardiovascular diseases (CVDs) using a multistate modeling framework. Patients and methods Data on 2600 patients with DLBCL diagnosed between 2000 and 2018 and had received chemotherapy with or without radiotherapy were obtained from a population-wide electronic…

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Cardiorespiratory Fitness and Bone Turnover Markers in Adults With Metabolic Syndrome: The Mediator Role of Inflammation

Artículos Científicos, Igualdad, Investigación, Mujeres EASP

The relationship between inflammatory markers and bone turnover in adults is well known, and a negative association between cardiorespiratory fitness (CRF) and inflammatory markers has also been described. Hence, we tested whether the association between CRF and bone turnover markers is mediated by inflammatory markers in adults with metabolic syndrome. A total of 81 adults…

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Cardiorespiratory Fitness and Bone Turnover Markers in Adults With Metabolic Syndrome: The Mediator Role of Inflammation

Cáncer, Igualdad, Investigación, Mujeres EASP

The relationship between inflammatory markers and bone turnover in adults is well known, and a negative association between cardiorespiratory fitness (CRF) and inflammatory markers has also been described. Hence, we tested whether the association between CRF and bone turnover markers is mediated by inflammatory markers in adults with metabolic syndrome. A total of 81 adults…

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Carbapenemase production and in-hospital mortality associated with multidrug-resistant bacteria: a retrospective study conducted in Granada, Spain

Artículos Científicos, Cáncer

Background Multidrug-resistant bacteria (MDR) represent a significant global health concern and vary in specific settings. Spain reported several annual deaths attributed to MDR bacteria, mainly carbapenemase-producing Enterobacterales. Objectives We aimed to characterise the incidence and temporal trends of MDR bacterial infections or colonisations reported within the province of Granada (data from five hospitals), and to…

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Características de los ‪ingresos hospitalarios‬ de las personas ‪‎sin hogar‬ en ‪Sevilla‬

Artículos Científicos

Fundamentos: Las personas sin hogar presentan una mayor morbi-mortalidad que las que sí lo tienen. Este hecho no ha sido investigado suficientemente en España desde la perspectiva de la atención hospitalaria. El objetivo fue conocer las características de las hospitalizaciones de las personas sin hogar en dos hospitales de Sevilla. Métodos: Estudio observacional de 103.802…

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Cancer Survival in Adults in Spain: A Population-Based Study of the Spanish Network of Cancer Registries (REDECAN)

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

The assessment of cancer survival at the population level is essential for monitoring progress in cancer control. We aimed to assess cancer survival and its trends in adults in Spain. Individual records of 601,250 adults with primary cancer diagnosed during 2002–2013 and followed up to 2015 were included from 13 population-based cancer registries. We estimated…

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Cancer survival in adult patients in Spain. Results from nine population-based cancer registries

Artículos Científicos

Introduction With the aim of providing cancer control indicators, this work presents cancer survival in adult (≥15 years) patients in Spain diagnosed during the period 2000–2007 from Spanish cancer registries participating in the EUROCARE project. Methods Cancer cases from nine Spanish population-based cancer registries were included and analysed as a whole. All primary malignant neoplasms diagnosed…