Childhood chromium exposure and neuropsychological development in children living in two polluted areas in southern Spain

This study aimed to assess the association between exposure to chromium and neuropsychological development among children. A cross-sectional study was conducted with 393 children aged 6–11 years old randomly selected from State-funded schools in two provinces in Southern Spain (Almeria and Huelva), in 2010 and 2012. Chromium levels in urine and hair samples were analyzed…

Childhood and adolescent lymphoma in Spain: incidence and survival trends over 20 years

Lymphoma is the third most common malignancy in children (0–14 years) and the first in adolescents (15–19 years). This population-based study—the largest ever done in Spain—analyses incidence and survival of lymphomas among Spanish children and adolescents. Patients and methods 1664 lymphoma cases (1983–2007) for incidence and 1030 for survival (1991–2005) followed until 31/12/2010, were provided by 11…

Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment

Background: Central nervous system (CNS) neoplasms are highly frequent solid tumours in children and adolescents. While some studies have shown a rise in their incidence in Europe, others have not. Survival remains limited. We addressed two questions about these tumours in Spain: (1) Is incidence increasing? and (2) Has survival improved? Methods: This population-based study…

Child Care Center Hand Hygiene Programs’ Cost-Effectiveness in Preventing Respiratory Infections

BACKGROUND We previously demonstrated that a hand hygiene program, including hand sanitizer and educational measures, for day care center (DCC) staff, children, and parents was more effective than a soap-and-water program, with initial observation, in preventing respiratory infections (RIs) in children attending DCCs. We analyzed the cost-effectiveness of these programs in preventing RIs. METHODS A…

Characterization of Cyberbullying Victimization and Perpetration Before and During the COVID-19 Pandemic in Spain

Cyberbullying is an extremely damaging form of interpersonal violence. Little is yet known about cyberbullying behaviors in the child and youth population during the COVID-19 pandemic and what effect this reduction in face-to-face social interactions has had on an increase in socialization via the Internet and cyberbullying. The present study is a cross-sectional descriptive study…

Changes in molecular biomarkers of neurotoxicity in newborns following prenatal exposure to organophosphate compounds

The rising incidence of neurodevelopmental disorders has been associated with early-life exposure to environmental factors, particularly neurotoxicants like organophosphate compounds (OPCs), which can impact brain development and function. This study examined the relationship between prenatal exposure to OPCs and molecular biomarkers of neurotoxicity in cord blood from 398 mother-child pairs in the GENEIDA birth cohort…

Changes in lifestyle and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition

Introduction: We investigated the impact of changes in lifestyle habits on colorectal cancer (CRC) risk in a multi-country European cohort. Methods: We used baseline and follow-up questionnaire data from the EPIC cohort to assess changes in lifestyle habits and their associations with CRC development. We calculated a healthy lifestyle index (HLI) score based on smoking…

Changes in Caregiver Personal Support Networks: Gender Differences and Effects on Health (CUIDAR-SE Study)

Technological changes have led to important advances in medical diagnoses and treatments that prolong the informal care process. Support from the personal network of informal caregivers is an undervalued resource and the changes that have occurred over time are unknown. The aim of this study was to analyze the changes in personal network support among…

Challenges for Economic Evaluations of Advanced Therapy Medicinal Products: A Systematic Review

Objectives Advanced therapy medicinal products (ATMPs) are drugs for human use for the treatment of chronic, degenerative, or life-threatening diseases that are based on genes, tissues, or cells. This article aimed to identify and critically review published economic analyses of ATMPs. Methods A systematic review of economic analyses of ATMPs was undertaken. Study characteristics, design,…

Centenary Personality: Are There Psychological Resources that Distinguish Centenarians?

The number of centenarians is increasing year by year. Considering that happier people are likely to live longer, we asked ourselves whether healthy centenarians share psychological resources or positive personality characteristics that have enabled them to face traumatic situations and the challenges life more successfully. To our knowledge this is an issue that has not…