Blood Metabolic Signatures of Body Mass Index: A Targeted Metabolomics Study in the EPIC Cohort

Metabolomics is now widely used to characterize metabolic phenotypes associated with lifestyle risk factors such as obesity. The objective of the present study was to explore the associations of body mass index (BMI) with 145 metabolites measured in blood samples in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Metabolites were measured in…

La activación de pacientes crónicos y su relación con el personal sanitario en Andalucía

Fundamento. Evaluar la (inter)relación entre la activación de pacientes crónicos y su relación con el personal sanitario en Andalucía. Material y métodos. Estudio cuantitativo realizado con 258  pacientes crónicos de la Escuela de Pacientes, que respondieron tras ser contactados por correo electrónico. De ellos, 142 completaron los cuestionarios. Se emplearon los cuestionarios Patient Activacion Measurement (PAM)…

Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study

Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data…

Determination of oleanolic acid in human plasma and its association with olive oil intake in healthy Spanish adults within the EPIC Spain cohort study

Scope Oleanolic acid (OA) is an important triterpenic compound found in olive oil, however little is known about its concentrations in human plasma. We aimed to determine plasma OA levels in a healthy Spanish population and compare them with estimates of dietary olive oil intake. Methods and results The final study sample included 141 individuals…

Barriers and enablers in the implementation of a program to reduce cesarean deliveries

Background Conducting audits, implementing best practices and giving feedback to the professionals have shown considerable promise in reducing rates of cesarean delivery and mother-child morbidity. The purpose of the study is two-fold: a) to identify the factors that facilitate change in current practices and thus reduce the use of obstetric interventions, and b) to better…

Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study

Background:The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective:To examine whether coffee consumption is associated with all-cause and cause-specific mortality. Design:Prospective cohort study. Setting:10 European countries. Participants:521 330 persons enrolled in EPIC (European Prospective Investigation into Cancer and Nutrition). Measurements:Hazard ratios (HRs) and 95% CIs estimated…

Health assessments for health governance: concepts and methodologies

Background: For better supporting the science-governance interface, the potential of health assessments appears underrated. Aims: To identify what various types of health assessment have in common; how they differ; which assessment(s) to apply for which purpose; and what needs and options there are for future joint development. Methods: This review is based on five types…

Hospital admissions due to alcohol related disorders among young adult refugees who arrived in Sweden as teenagers – a national cohort study

Background Psychological distress and lack of family support may explain the mental health problems that are consistently found in young unaccompanied refugees in Western countries. Given the strong relationship between poor mental health and alcohol misuse, this study investigated hospital admissions due to alcohol related disorders among accompanied and unaccompanied young refugees who settled in…

Tendencia de la obesidad infantil y el bajo peso por año de nacimiento y edad en España, 1983-2011

Introducción y objetivos Las prevalencias de obesidad infantil y sobrepeso están en aumento en todo el mundo y representan un importante problema de salud pública, especialmente en los perfiles de riesgo cardiovascular en la edad adulta si la obesidad no se revierte. La identificación precisa de las tendencias y los subgrupos en riesgo es crucial…