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Contribution of Persistent Organic Pollutant Exposure to the Adipose Tissue Oxidative Microenvironment in an Adult Cohort: A Multipollutant Approach

Artículos Científicos

Despite growing in vitro and in vivo evidence of the putative role of persistent organic pollutants (POPs) in the induction of oxidative damage in cell structures, this issue has been poorly addressed from an epidemiologic perspective. The aim of this study was to explore associations between adipose tissue POP concentrations and the in situ oxidative…

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Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study

Artículos Científicos

Background There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity. Methods This prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from…

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Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into cancer and Nutrition

Artículos Científicos

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate…

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Consumption of Meat, Fish, Dairy Products, Eggs and Risk of Ischemic Heart Disease: A Prospective Study of 7198 Incident Cases Among 409,885 Participants in the Pan-European EPIC Cohort

Artículos Científicos

Background: There is uncertainty about the relevance of animal foods to the etiology of ischemic heart disease (IHD). We examined meat, fish, dairy products and eggs and risk for IHD in the pan-European EPIC cohort. Methods: A prospective study of 409,885 men and women in nine European countries. Diet was assessed using validated questionnaires, calibrated…

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Consumption of fruits, vegetables and fruit juices and differentiated thyroid carcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Artículos Científicos

Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid cancer (TC). The purpose of this study is to examine the association between the consumption of fruits, vegetables, fruit juices and differentiated thyroid cancer risk within the European Prospective Investigation into…

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Consumption of Fish Is Not Associated with Risk of Differentiated Thyroid Carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study

Artículos Científicos

Background: Differentiated thyroid cancer (TC) is the most common endocrine cancer. Fish can be an important source of iodine and other micronutrients and contaminants that may affect the thyroid gland and TC risk. Objective: We prospectively evaluated the relations between the consumption of total fish and different fish types and shellfish and TC risk in…

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Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort

Artículos Científicos

Background & Aims There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and…

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Consideraciones de seguridad en la prescripción de medicamentos antiinflamatorios no esteroideos (AINEs), a través de una revisión de revisiones sistemáticas

Artículos Científicos

Los medicamentos antiinflamatorios no esteroideos (AINEs) se encuentran entre los medicamentos más consumidos mundialmente. Esto hace necesario realizar una síntesis amplia de la evidencia disponible sobre la prescripción segura y adecuada de AINEs en pacientes con enfermedad cardiovascular, enfermedad renal crónica, hipertensión, insuficiencia cardíaca o cirrosis hepática y en población general. Para ello se ha…

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Conocimientos y actitudes de los médicos de Atención Primaria de Andalucía (España) sobre la detección de personas con riesgo elevado de cáncer de mama y colorrectal

Artículos Científicos

Objetivos Explorar los conocimientos y las actitudes de los médicos de Atención Primaria de Andalucía sobre la detección de personas con riego elevado de cáncer de mama y colorrectal y el cáncer hereditario. Métodos Estudio descriptivo transversal a partir de una encuesta de opinión on line. Cuestionario de 24 preguntas. Para el análisis estadístico se…