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Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test. Methods We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 years…

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Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test. Methods We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 years…

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Los vídeos como herramienta de difusión científica y transferencia de conocimiento

Artículos Científicos

La investigación científica no puede dar la espalda a los nuevos hábitos de consumo de la información. En este nuevo escenario donde está disminuyendo de manera generalizada la capacidad de atención, las nuevas generaciones utilizan cada vez con más frecuencia el vídeo como herramienta clave para el acceso al conocimiento. En este sentido, parece oportuno,…

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Long-term survival for lymphoid neoplasms and national health expenditure (EUROCARE-6): a retrospective, population-based study

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Background Management of lymphoid malignancies requires substantial health system resources. Total national health expenditure might influence population-based lymphoid malignancy survival. We studied the long-term survival of patients with 12 lymphoid malignancy types and examined whether different levels of national health expenditure might explain differences in lymphoid malignancy prognosis between European countries and regions. Methods For…

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Living with disabling chronic pain: results from a face-to-face cross-sectional population-based study

Artículos Científicos

Objectives To estimate the prevalence of disabling chronic pain (DCP) in Spanish adults, to analyse its characteristics, to determine its multimorbidity and to identify its associated factors. Settings 2011 Andalusian Health Survey, a cross-sectional population survey based on face-to-face home interviews. Participants 6507 people aged 16 years or older and living in Andalusia, Spain. Outcomes…

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Lipopolysaccharide-binding protein and future Parkinson’s disease risk: a European prospective cohort

Artículos Científicos, Cáncer, Investigación, Mujeres EASP

Introduction Lipopolysaccharide (LPS) is the outer membrane component of Gram-negative bacteria. LPS-binding protein (LBP) is an acute-phase reactant that mediates immune responses triggered by LPS and has been used as a blood marker for LPS. LBP has recently been indicated to be associated with Parkinson’s disease (PD) in small-scale retrospective case–control studies. We aimed to…

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Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies

Artículos Científicos

Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long‐term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer…

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Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study

Artículos Científicos

Background Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely investigated. The aim of this study was to investigate associations between five lifestyle factors and incident multimorbidity of cancer and cardiometabolic diseases. Methods In this prospective cohort…