Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization

Background Accelerated reproductive aging, in women indicated by early natural menopause, is associated with increased coronary heart disease (CHD) risk in observational studies. Conversely, an adverse CHD risk profile has been suggested to accelerate menopause. Objectives To study the direction and evidence for causality of the relationship between reproductive aging and (non-)fatal CHD and CHD…

Public Perception of Organ Donation and Transplantation Policies in Southern Spain

This research explores how public awareness and attitudes toward donation and transplantation policies may contribute to Spain’s success in cadaveric organ donation. Materials and Methods A representative sample of 813 people residing in Andalusia (Southern Spain) were surveyed by telephone or via Internet between October and December 2018. Results Most participants trust Spain’s donation and…

Cross-Cultural Adaptation, Validation, and Piloting of the Patient Reported Experiences and Outcomes of Safety in Primary Care Questionnaire for Its Use in Spain

Objective This study aimed to cross-culturally adapt, validate, and pilot the Patient Reported Experiences and Outcomes of Safety in Primary Care questionnaire for its use in Spain. Methods After setting up an expert panel to determine its content validity, the questionnaire was translated and back-translated, and subjected to cognitive testing. The questionnaire was piloted in…

Autocuidado ético y emocional para sanitariosEthical and emotional self-care for health professionals

La pandemia de la COVID-19 ha puesto de relieve, una vez más, las carencias con relación a las habilidades para el autocuidado ético y emocional por parte de los profesionales sanitarios de este país. En la presente colaboración se revisan brevemente algunas de las iniciativas realizadas para paliar dicha carencia, se sugieren diversas preguntas esenciales…

Feasibility of the SINERGIAPS (“Sinergias entre profesionales y pacientes para una Atención Primaria Segura”) intervention for improving patient safety in primary care

Aim The primary aim was to examine the feasibility of intervention delivery and of trial procedures. Secondary aims were to study the intervention uptake; its acceptability and perceived utility; and its potential to improve safety culture and avoidable hospital admissions. Methods We conducted a 3-month, single-arm feasibility study in 10 primary care (PC) centres in…

Description of day case costs and tariffs of cataract surgery from a sample of nine European countries

Background The lack of transparency in the methodology of unit cost estimation and the usage of confidential or undisclosed information prevents cost comparisons and makes the transferability of the results across countries difficult. The objective of this article is to compare the methodologies used in the estimation of the cost of a day case cataract…

The Role of Indication-Based Pricing in Future Pricing and Reimbursement Policies: A Systematic Review

Objectives Indication-based pricing (IBP) has received growing attention because of the expected increase in the number of new medicines with multiple indications. In our systematic review, we assess the potential benefits, barriers, current experiences, and future perspectives of different IBP mechanisms. Methods We searched publications in English, Spanish, or French assessing the impact, international experience,…

Are costs derived from diagnosis-related groups suitable for use in economic evaluations? A comparison across nine European countries in the European Healthcare and Social Cost Database

Background Economic evaluation of health technologies requires healthcare resources, procedures and services to be valued at their opportunity cost. In practice, many economic evaluation studies use official databases of hospital Diagnosis-Related Groups (DRGs) as inputs where unit costs are required. This study describes the available data on costs of hospital DRG from official, publicly available…

Gender and Social Inequalities in Awareness of Coronary Artery Disease in European Countries

Coronary artery disease (CAD) is the single leading cause of death in Europe and the most common form of cardiovascular disease. Little is known about awareness in the European population. A cross-sectional telephone survey of 2609 individuals from six European countries was conducted to gather information on perceptions of CAD, risk factors, preventive measures, knowledge…