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Prognostic role of pre-diagnostic circulating inflammatory biomarkers in breast cancer survival: evidence from the EPIC cohort study

Artículos Científicos, Cáncer, Igualdad, Investigación, Mujeres EASP

Background Inflammation influences tumour progression and cancer prognosis, but its role preceding breast cancer (BC) and its prognostic implications remain inconclusive. Methods We studied pre-diagnostic plasma inflammatory biomarkers in 1538 women with BC from the EPIC study. Cox proportional hazards models assessed their relationship with all-cause and BC-specific mortality, adjusting for tumour characteristics and lifestyle…

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Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study

Artículos Científicos

Background Head and neck (H&N) cancers are a heterogeneous group of malignancies, affecting various sites, with different prognoses. The aims of this study are to analyse survival for patients with H&N cancers in relation to tumour location, to assess the change in survival between European countries, and to investigate whether survival improved over time. Methods…

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Process evaluation of PsyCovidApp, a digital tool for mobile devices aimed at protecting the mental health of healthcare professionals during the COVID-19 pandemic: a mixed method study

Artículos Científicos, Investigación, Mujeres EASP

Introduction: PsyCovidApp, a digital intervention aimed at safeguarding the mental health of healthcare workers during the COVID-19 pandemic, demonstrated in a randomized clinical trial to yield significant improvements solely among healthcare workers undergoing psychotherapy or receiving psychotropic medication. Objectives: (1) To identify contextual factors and mechanisms of action that influenced the impact of PsyCovidApp during…

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Prisons and custodial settings are part of a comprehensive response to COVID-19

Artículos Científicos

Prisons are epicentres for infectious diseases because of the higher background prevalence of infection, the higher levels of risk factors for infection, the unavoidable close contact in often overcrowded, poorly ventilated, and unsanitary facilities, and the poor access to health-care services relative to that in community settings. 1 Infections can be transmitted between prisoners, staff…

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Priorización de actividades clínicas no recomendadas en Atención Primaria

Artículos Científicos

Fundamento. Priorización de las recomendaciones “no hacer” procedentes de la lista de la Sociedad Española de Medicina de Familia y Comunitaria (Semfyc) de actividades preventivas, diagnósticas, terapéuticas o de cuidados que no es correcto hacer en Atención Primaria (AP), a través de un consenso de profesionales expertos de medicina, farmacia y enfermería. Método. Mediante un…

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Priorities for health economic methodological research: results of an expert consultation

Artículos Científicos

Background: The importance of economic evaluation in decision making is growing with increasing budgetary pressures on health systems. Diverse economic evidence is available for a range of interventions across national contexts within Europe, but little attention has been given to identifying evidence gaps that, if filled, could contribute to more efficient allocation of resources. One…

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Priorities and needs for research on urban interventions targeting vector-borne diseases: rapid review of scoping and systematic reviews

Artículos Científicos

This paper highlights the critical importance of evidence on vector-borne diseases (VBD) prevention and control interventions in urban settings when assessing current and future needs, with a view to setting policy priorities that promote inclusive and equitable urban health services. Research should produce knowledge about policies and interventions that are intended to control and prevent…

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Pricing and reimbursement mechanisms for advanced therapy medicinal products in 20 countries

Artículos Científicos

Introduction: Advanced Therapy Medicinal Products are a type of therapies that, in some cases, hold great potential for patients without an effective current therapeutic approach but they also present multiple challenges to payers. While there are many theoretical papers on pricing and reimbursement (P&R) options, original empirical research is very scarce. This paper aims to…

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Prevención primaria de enfermedades cardiovasculares: una revisión de revisiones de intervenciones no farmacológicas

Artículos Científicos

Fundamento. El objetivo de este estudio es determinar la efectividad de intervenciones no farmacológicas para la prevención de eventos relacionados con enfermedad cardiovascular (CVD), y mortalidad en adultos sanos o con alto riesgo de CVD. Método. Revisión de revisiones sobre prevención primaria de intervenciones no farmacológicas en las bases de datos de PubMed Health, Effective…